Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 6/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27885016 | 0.82 | HASPIN (0.40) | MCL1PTPN1 | |
| SCHEMBL27917591 | 0.81 | MCL1 (0.62) | MCL1CYP19A1DYRK1AMEN1KMT2A | |
| SCHEMBL27899812 | 0.80 | MCL1 (0.48) | MCL1CYP19A1DYRK1AMEN1HTT | |
| Bromide SCHEMBL27899810 | 0.79 | MCL1 (0.47) | MCL1CYP19A1DYRK1AMEN1HTT | |
| SCHEMBL27917595 | 0.78 | MCL1 (0.63) | MCL1CYP19A1DYRK1AMEN1KMT2A | |
| SCHEMBL27917526 | 0.76 | KDM4E (0.49) | MCL1DYRK1AHTTKMT2A | |
| SCHEMBL27899842 | 0.74 | KDM4E (0.51) | MCL1HTT | |
| SCHEMBL27899816 | 0.72 | P2RX4 (0.52) | MCL1CYP19A1DYRK1AHTTKMT2A | |
| SCHEMBL232662 | 0.67 | ACHE (0.49) | PARP1AR | |
| SCHEMBL29373118 | 0.67 | ACHE (0.49) | PARP1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114191432-A | Application of harmine derivative in preparation of anti-hydatid insecticide | 新疆医科大学第一附属医院 | 2022-03-18 | — | — | CN | claimed |
| CN-114191432-A | Application of harmine derivative in preparation of anti-hydatid insecticide | 新疆医科大学第一附属医院 | 2022-03-18 | — | — | CN | disclosed |