Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MDH1 | P40925 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482843 | 0.88 | KMT2A (0.41) | KMT2AMAPTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL2888364 | 0.86 | MAPT (0.40) | KMT2AMAPTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL2506912 | 0.85 | MAPT (0.40) | KMT2AMAPTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL498389 | 0.85 | MAPT (0.55) | KMT2AMAPTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL2888400 | 0.84 | NPSR1 (0.41) | KMT2AMAPTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL2888081 | 0.83 | NPSR1 (0.38) | KMT2AMAPTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL2508302 | 0.83 | TDP1 (0.49) | KMT2AMAPTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL2507012 | 0.83 | NPSR1 (0.40) | KMT2AMAPTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL2512726 | 0.82 | KMT2A (0.38) | KMT2AMAPTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL2509134 | 0.81 | PTGDR2 (0.38) | KMT2AMAPTSMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9464144-B2 | Enhanced procatalyst composition and process | W. R. Grace & Co.—Conn. (US) | 2016-10-11 | — | — | US | disclosed |
| US-9464144-B2 | Enhanced procatalyst composition and process | W. R. Grace & Co.—Conn. (US) | 2016-10-11 | — | — | US | disclosed |
| EP-2373701-B1 | ENHANCED PROCATALYST COMPOSITION AND PROCESS | GRACE W R & CO (US) | 2016-03-09 | — | — | EP | disclosed |
| US-20140274668-A1 | ENHANCED PROCATALYST COMPOSITION AND PROCESS | W. R. GRACE & CO.-CONN. (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140274668-A1 | ENHANCED PROCATALYST COMPOSITION AND PROCESS | W. R. GRACE & CO.-CONN. (US) | 2014-09-18 | — | — | US | disclosed |
| US-8778826-B2 | Enhanced procatalyst composition and process | W. R. GRACE & CO.-CONN. (US) | 2014-07-15 | — | — | US | disclosed |
| US-8778826-B2 | Enhanced procatalyst composition and process | W. R. GRACE & CO.-CONN. (US) | 2014-07-15 | — | — | US | disclosed |
| US-8604235-B2 | Production of substituted phenylene aromatic diesters and compositions | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-10 | — | — | US | disclosed |
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | W. R. GRACE & CO.-CONN. | 2010-08-12 | — | — | US | disclosed |
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | W. R. GRACE & CO.-CONN. | 2010-08-12 | — | — | US | disclosed |
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | W. R. GRACE & CO.-CONN. | 2010-08-12 | — | — | US | disclosed |
| WO-2010078519-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| US-20100173769-A1 | Enhanced Procatalyst Composition and Process | W. R. GRACE & CO.-CONN. | 2010-07-08 | — | — | US | disclosed |
| US-20100173769-A1 | Enhanced Procatalyst Composition and Process | W. R. GRACE & CO.-CONN. | 2010-07-08 | — | — | US | disclosed |
| WO-2010078503-A1 | ENHANCED PROCATALYST COMPOSITION AND PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | PAH, DDC, DDT | KMT2A 1611/4885MAPT 2384/4885SMN1; SMN2 4422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.