Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482843 | 0.89 | KMT2A (0.41) | NPSR1MAPTKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2483580 | 0.89 | L3MBTL1 (0.47) | NPSR1MAPTKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2888400 | 0.85 | NPSR1 (0.41) | NPSR1MAPTKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2506912 | 0.84 | MAPT (0.40) | NPSR1MAPTKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2886891 | 0.83 | KMT2A (0.43) | NPSR1MAPTKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2507012 | 0.83 | NPSR1 (0.40) | NPSR1MAPTKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2888364 | 0.81 | MAPT (0.40) | NPSR1MAPTKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2510094 | 0.80 | KMT2A (0.44) | MAPTKMT2ASMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL2476875 | 0.80 | MAPT (0.41) | MAPTKMT2ASMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL2480077 | 0.79 | KMT2A (0.43) | MAPTKMT2ASMN1; SMN2L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8604235-B2 | Production of substituted phenylene aromatic diesters and compositions | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-10 | — | — | US | disclosed |
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | W. R. GRACE & CO.-CONN. | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | PAH, DDC, DDT | NPSR1 2230/4885MAPT 2384/4885KMT2A 1611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.