Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26581400 | 0.85 | ATM (0.55) | ALKBH5FTOEGFRATMKMT2A | |
| SCHEMBL6671401 | 0.76 | EGFR (0.66) | EGFRSRCKMT2AMEN1ALDH1A1 | |
| SCHEMBL29414698 | 0.76 | EGFR (0.66) | EGFRSRCKMT2AMEN1ALDH1A1 | |
| SCHEMBL28268477 | 0.73 | EGFR (0.43) | ALKBH5FTOEGFRSRCKMT2A | |
| SCHEMBL28115226 | 0.73 | ALKBH5 (0.46) | ALKBH5FTOEGFRSRCKMT2A | |
| SCHEMBL30583770 | 0.72 | ALKBH5 (0.57) | ALKBH5FTOATMKMT2AMEN1 | |
| SCHEMBL25534616 | 0.72 | ALKBH5 (0.57) | ALKBH5FTOATMKMT2AMEN1 | |
| SCHEMBL311565 | 0.71 | PARP1 (0.46) | KMT2AMEN1EPHB4ALDH1A1BLM | |
| SCHEMBL14931058 | 0.71 | ALKBH5 (0.72) | ALKBH5FTOATMKMT2AMEN1 | |
| SCHEMBL7268507 | 0.70 | KDM4E (0.41) | ALKBH5FTOKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459030-B | Replace tropane derivatives | 东亚荣养株式会社 | 2019-01-29 | — | — | CN | claimed |