Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115225 | 0.83 | EGFR (0.41) | EGFRSRCNPC1SMN1; SMN2MAPT | |
| SCHEMBL4106684 | 0.76 | EGFR (0.68) | EGFRSRCNPC1SMN1; SMN2MAPT | |
| SCHEMBL26581400 | 0.75 | ATM (0.55) | ALKBH5FTOEGFRRORCNPC1 | |
| SCHEMBL28868912 | 0.73 | ALKBH5 (0.46) | ALKBH5FTOEGFRSRCRORC | |
| SCHEMBL14931058 | 0.71 | ALKBH5 (0.72) | ALKBH5FTONPC1MAPTALDH1A1 | |
| SCHEMBL19276580 | 0.71 | NQO2 (0.48) | ALKBH5FTORORCNPC1MAPT | |
| SCHEMBL22450932 | 0.69 | MAPT (0.48) | EGFRSRCNPC1SMN1; SMN2MAPT | |
| SCHEMBL696352 | 0.69 | THRB (0.56) | NPC1SMN1; SMN2ALDH1A1RAB9ABRPF1 | |
| SCHEMBL13100052 | 0.69 | ALDH1A1 (0.52) | NPC1ALDH1A1KMT2AHCRTR1RAB9A | |
| SCHEMBL12536109 | 0.68 | BRD4 (0.56) | ALKBH5FTORORCNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105001220-B | Preparation method of indoloquinoline alkaloid analogues | 渤海大学 | 2017-01-11 | — | — | CN | disclosed |