Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28647892 | 0.71 | ALDH1A1 (0.50) | — | |
| SCHEMBL27866631 | 0.71 | HCAR2 (0.38) | HCAR2 | |
| SCHEMBL28059802 | 0.71 | HCAR2 (0.38) | HCAR2 | |
| SCHEMBL11058677 | 0.71 | HCAR2 (0.38) | HCAR2 | |
| SCHEMBL28189368 | 0.71 | HCAR2 (0.38) | HCAR2 | |
| SCHEMBL4763042 | 0.68 | HTT (0.45) | HCAR2 | |
| SCHEMBL23246120 | 0.67 | HCAR2 (0.34) | HCAR2 | |
| SCHEMBL27708874 | 0.65 | HCAR2 (0.33) | HCAR2 | |
| SCHEMBL3430030 | 0.65 | NPSR1 (0.47) | HCAR2 | |
| SCHEMBL29108038 | 0.65 | KMT2A (0.31) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109312339-A | Materials and methods for treating amyotrophic lateral sclerosis and/or frontotemporal lobar degeneration | 克里斯珀医疗股份公司 | 2019-02-05 | — | — | CN | disclosed |