SCHEMBL28059802

SCHEMBL28059802

NC(=O)N(Br)c1cncnc1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.38
AR P10275 1/20 0.33
GRM5 P41594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28189368 0.78 HCAR2 (0.38) HCAR2ARGRM5
SCHEMBL11058677 0.74 HCAR2 (0.38) HCAR2
SCHEMBL27866631 0.74 HCAR2 (0.38) HCAR2
SCHEMBL28869155 0.71 HCAR2 (0.35) HCAR2
SCHEMBL23246120 0.69 HCAR2 (0.34) HCAR2AR
SCHEMBL8393643 0.68 NPSR1 (0.46)
SCHEMBL27708874 0.68 HCAR2 (0.33) HCAR2
SCHEMBL3430030 0.68 NPSR1 (0.47) HCAR2
SCHEMBL432934 0.67 HCAR2 (0.44) HCAR2ARGRM5
SCHEMBL27810412 0.67 HCAR2 (0.44) HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109485730-A Anti- CD22 Chimeric antigen receptor 美国卫生和人力服务部 2019-03-19 CN disclosed
CN-109153697-A Mono- GalNAc compound of trityl-and application thereof 豪夫迈·罗氏有限公司 2019-01-04 CN disclosed
CN-102712671-B Phospholipase, the nucleic acid encoding it and preparation and their method of use 帝斯曼知识产权资产管理有限公司 2016-11-09 CN disclosed
CN-104491852-B Tumor DNA vaccine with MUC-1 and survivin as target spot and vector-viral vaccine 长春百克生物科技股份公司 2016-08-03 CN disclosed