Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 8/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432934 | 0.80 | HCAR2 (0.44) | HCAR2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL28059802 | 0.78 | HCAR2 (0.38) | HCAR2GRM5AR | |
| SCHEMBL27969677 | 0.78 | CA12 (0.32) | ALDH1A1KMT2A | |
| SCHEMBL1577273 | 0.76 | NOTUM (0.50) | HCAR2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL28003019 | 0.75 | ALOX15 (0.38) | HCAR2ALDH1A1KDM4EKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL17785084 | 0.75 | NOTUM (0.49) | HCAR2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL11058677 | 0.74 | HCAR2 (0.38) | HCAR2 | |
| SCHEMBL27866631 | 0.74 | HCAR2 (0.38) | HCAR2 | |
| SCHEMBL23246120 | 0.74 | HCAR2 (0.34) | HCAR2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL28869155 | 0.71 | HCAR2 (0.35) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105638695-B | A kind of polyoxin pulvis and preparation method thereof | 牡丹江佰佳信生物科技有限公司 | 2017-12-26 | — | — | CN | claimed |
| CN-105670979-B | Nucleoside phosphorylase, coding gene, high-yield strain thereof and application | 南京工业大学 | 2019-03-26 | — | — | CN | disclosed |
| CN-108358927-A | 1,4- bis- replaces 1,2,3- ribavirin analogs and its preparation method and application | 郑州大学 | 2018-08-03 | — | — | CN | disclosed |
| CN-105638695-B | A kind of polyoxin pulvis and preparation method thereof | 牡丹江佰佳信生物科技有限公司 | 2017-12-26 | — | — | CN | disclosed |