Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.51 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 14/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7830642 | 0.86 | KMO (0.56) | AR | |
| SCHEMBL28869486 | 0.82 | MKNK1 (0.51) | ARPARP1 | |
| SCHEMBL7815823 | 0.82 | RAB9A (0.49) | PDK2NPC1RAB9A | |
| SCHEMBL5307077 | 0.80 | PARP1 (0.56) | BAZ2BBAZ2APARP1PDK2NPC1 | |
| SCHEMBL27921662 | 0.79 | AR (0.51) | AR | |
| SCHEMBL18076320 | 0.79 | KDM4E (0.50) | NPC1RAB9A | |
| SCHEMBL3636122 | 0.79 | NR1H4 (0.56) | BAZ2BBAZ2ABRD4PARP1PDK2 | |
| SCHEMBL3785593 | 0.77 | BAZ2B (0.52) | BAZ2BBAZ2APARP1PDK2NPC1 | |
| SCHEMBL28096188 | 0.77 | BCAT2 (0.67) | BAZ2BBAZ2APARP1PDK2NPC1 | |
| SCHEMBL3164816 | 0.76 | BAZ2B (0.52) | BAZ2BBAZ2ABRD4PARP1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369504-A | The preparation method of sulfur-bearing 3- methylene 1-isoindolinone derivative | 温州大学 | 2019-02-22 | — | — | CN | disclosed |