Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 9/20 | 0.59 |
| ▸ | RAB9A | P51151 | 9/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.59 |
| ▸ | RELA | Q04206 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.55 |
| ▸ | TUBB | P07437 | 3/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1544017 | 0.86 | MAPT (0.65) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL30639490 | 0.83 | HTR6 (0.59) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL27033031 | 0.83 | HTR6 (0.59) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL14788168 | 0.82 | SIRT2 (0.74) | MAPTSMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL14946435 | 0.81 | MAPT (0.69) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL28957095 | 0.81 | RAB9A (0.68) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL103242 | 0.80 | MAPT (0.58) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL6324681 | 0.79 | FFAR1 (0.75) | MAPTSMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL16067423 | 0.79 | L3MBTL1 (0.72) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL6323754 | 0.78 | HTT (0.67) | MAPTSMN1; SMN2MEN1KMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093377-A | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2022-09-23 | — | — | CN | claimed |
| CN-115093377-B | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115093377-A | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2022-09-23 | — | — | CN | disclosed |