Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 10/20 | 0.65 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | JAK1 | P23458 | 1/20 | 0.59 |
| ▸ | TYK2 | P29597 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.52 |
| ▸ | ITGAL | P20701 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992219 | 0.86 | CES2 (0.58) | GAAJAK2JAK1TYK2LMNA | |
| SCHEMBL11005407 | 0.86 | ALDH1A1 (0.56) | GAAJAK2JAK1TYK2MAPT | |
| SCHEMBL19648317 | 0.85 | GAA (0.65) | GAAJAK2JAK1TYK2MAPT | |
| Hydrochloric Acid SCHEMBL29044162 | 0.84 | ALDH1A1 (0.54) | GAAJAK2JAK1TYK2MAPT | |
| SCHEMBL25051950 | 0.83 | GAA (0.63) | GAAJAK2JAK1TYK2MAPT | |
| SCHEMBL14968580 | 0.83 | GAA (0.63) | GAAJAK2JAK1TYK2MAPT | |
| SCHEMBL18306503 | 0.83 | GAA (0.63) | GAAJAK2JAK1TYK2MAPT | |
| SCHEMBL11098006 | 0.81 | GAA (0.61) | GAAJAK2JAK1TYK2MAPT | |
| SCHEMBL11100266 | 0.81 | GAA (0.61) | GAAJAK2JAK1TYK2MAPT | |
| Hydrochloric Acid SCHEMBL11098010 | 0.80 | GAA (0.59) | GAAJAK2JAK1TYK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093377-B | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115093377-A | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2022-09-23 | — | — | CN | disclosed |