Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4674384 | 0.86 | PTGS2 (0.42) | PDPK1HSD11B1PTGS1KMT2AMAPK9 | |
| SCHEMBL28869832 | 0.85 | KMT2A (0.48) | PDPK1PTGS1KMT2AMAPK9MAPK10 | |
| SCHEMBL28957164 | 0.84 | SMN1; SMN2 (0.54) | PTGS1KMT2ASMN1; SMN2CYP1A2NPC1 | |
| SCHEMBL4671357 | 0.84 | PDPK1 (0.54) | PDPK1PTGS1 | |
| SCHEMBL4674149 | 0.84 | PDPK1 (0.69) | PDPK1PTGS1LMNA | |
| SCHEMBL28869829 | 0.81 | SMN1; SMN2 (0.44) | PTGS1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL5865649 | 0.80 | PTGS2 (0.60) | PTGS1SMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL1115174 | 0.79 | HSD11B1 (0.39) | PDPK1HSD11B1PTGS1KMT2AOPRD1 | |
| SCHEMBL4671346 | 0.78 | HSD11B1 (0.42) | PDPK1HSD11B1PTGS1KMT2ASMN1; SMN2 | |
| SCHEMBL17011134 | 0.78 | KDM4A (0.43) | KMT2AOPRD1MAPK9MAPK10MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093373-A | 1, 5-disubstituted-3-fluoroalkyl-1, 2, 4-triazole compound and preparation method and application thereof | 江苏省中国科学院植物研究所 | 2022-09-23 | — | — | CN | disclosed |