Histidine

Histidine

SCHEMBL28870433

CC(C)CC(N)C(=O)O.NC(Cc1c[nH]cn1)C(=O)O.[Zn]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.50
SLC1A3 P43003 4/20 0.41
SLC1A2 P43004 4/20 0.41
CYP3A4 P08684 1/20 0.39
CYP1A2 P05177 1/20 0.38
ANPEP P15144 1/20 0.37
RNPEP Q9H4A4 1/20 0.37
DNPEP Q9ULA0 1/20 0.37
GRIA1 P42261 4/20 0.37
GRIA2 P42262 4/20 0.37
GRIA3 P42263 4/20 0.37
GRIA4 P48058 4/20 0.37
SLC1A1 P43005 3/20 0.36
LARS1 Q9P2J5 2/20 0.35
ALPI P09923 1/20 0.35
PKM P14618 1/20 0.35
PTGS1 P23219 1/20 0.35
XIAP P98170 1/20 0.35
GRIK1 P39086 3/20 0.34
GRM2 Q14416 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Histidine SCHEMBL716108 0.99 SLC7A5 (0.51) SLC7A5SLC1A3SLC1A2CYP3A4CYP1A2
Histidine SCHEMBL716109 0.99 SLC7A5 (0.51) SLC7A5SLC1A3SLC1A2CYP3A4CYP1A2
Histidine SCHEMBL1537416 0.99 SLC7A5 (0.51) SLC7A5SLC1A3SLC1A2CYP3A4CYP1A2
Histidine SCHEMBL21925063 0.96 SLC7A5 (0.49) SLC7A5SLC1A3SLC1A2CYP3A4CYP1A2
Histidine SCHEMBL5072093 0.96 SLC7A5 (0.49) SLC7A5SLC1A3SLC1A2CYP3A4CYP1A2
Histidine SCHEMBL21774926 0.93 SLC7A5 (0.46) SLC7A5SLC1A3SLC1A2CYP3A4CYP1A2
Histidine SCHEMBL26967573 0.93 SLC7A5 (0.46) SLC7A5SLC1A3SLC1A2CYP3A4CYP1A2
Histidine SCHEMBL21638967 0.92 SLC7A5 (0.45) SLC7A5SLC1A3SLC1A2CYP3A4CYP1A2
Histidine SCHEMBL245022 0.92 SLC7A5 (0.45) SLC7A5SLC1A3SLC1A2CYP3A4CYP1A2
Phenylalanine SCHEMBL14631617 0.90 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2ANPEPRNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109430478-A A kind of zinc selenium composite instant tea and preparation method thereof 湖北惠普美乐健康产业有限公司 2019-03-08 CN disclosed