Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.36 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL21925063 | 1.00 | SLC7A5 (0.49) | SLC7A5SLC1A3SLC1A2CYP3A4CYP1A2 | |
| Histidine SCHEMBL1537416 | 0.97 | SLC7A5 (0.51) | SLC7A5SLC1A3SLC1A2CYP3A4CYP1A2 | |
| Histidine SCHEMBL716108 | 0.97 | SLC7A5 (0.51) | SLC7A5SLC1A3SLC1A2CYP3A4CYP1A2 | |
| Histidine SCHEMBL716109 | 0.97 | SLC7A5 (0.51) | SLC7A5SLC1A3SLC1A2CYP3A4CYP1A2 | |
| Histidine SCHEMBL28870433 | 0.96 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2CYP3A4CYP1A2 | |
| Histidine SCHEMBL3335322 | 0.93 | SLC7A5 (0.43) | SLC7A5CYP3A4CYP1A2GRIA1GRIA2 | |
| Histidine SCHEMBL4610837 | 0.93 | SLC7A5 (0.43) | SLC7A5CYP3A4CYP1A2GRIA1GRIA2 | |
| Histidine SCHEMBL3457996 | 0.93 | SLC7A5 (0.43) | SLC7A5CYP3A4CYP1A2GRIA1GRIA2 | |
| Histidine SCHEMBL21774926 | 0.92 | SLC7A5 (0.46) | SLC7A5SLC1A3SLC1A2CYP3A4CYP1A2 | |
| Histidine SCHEMBL26967573 | 0.92 | SLC7A5 (0.46) | SLC7A5SLC1A3SLC1A2CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080063601-A1 | Compositions and methods relating to polycystic kidney disease | YALE UNIVERSITY (US) | 2008-03-13 | — | — | US | disclosed |