Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669156 | 1.00 | BLM (0.41) | BLMTSHRNFKB1SLC6A2SLC6A4 | |
| SCHEMBL8039415 | 0.97 | — | — | |
| SCHEMBL1503403 | 0.90 | — | — | |
| SCHEMBL13716727 | 0.80 | — | — | |
| SCHEMBL3921569 | 0.78 | — | — | |
| SCHEMBL5597865 | 0.78 | OPRM1 (0.48) | BLMTSHRNFKB1SLC6A2SLC6A4 | |
| SCHEMBL7653269 | 0.78 | OPRM1 (0.48) | BLMTSHRNFKB1SLC6A2SLC6A4 | |
| SCHEMBL544296 | 0.78 | SLC6A2 (0.45) | BLMTSHRNFKB1SLC6A2SLC6A4 | |
| SCHEMBL4373552 | 0.78 | OPRM1 (0.48) | BLMTSHRNFKB1SLC6A2SLC6A4 | |
| SCHEMBL11219189 | 0.78 | OPRM1 (0.48) | BLMTSHRNFKB1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109475593-A | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | 豪夫迈·罗氏有限公司 | 2019-03-15 | — | — | CN | disclosed |