Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28870655 | 1.00 | BLM (0.41) | BLMTSHRNFKB1SLC6A2SLC6A4 | |
| SCHEMBL8039415 | 0.97 | — | — | |
| SCHEMBL1503403 | 0.90 | — | — | |
| SCHEMBL13716727 | 0.80 | — | — | |
| SCHEMBL3921569 | 0.78 | — | — | |
| SCHEMBL5597865 | 0.78 | OPRM1 (0.48) | BLMTSHRNFKB1SLC6A2SLC6A4 | |
| SCHEMBL7653269 | 0.78 | OPRM1 (0.48) | BLMTSHRNFKB1SLC6A2SLC6A4 | |
| SCHEMBL544296 | 0.78 | SLC6A2 (0.45) | BLMTSHRNFKB1SLC6A2SLC6A4 | |
| SCHEMBL4373552 | 0.78 | OPRM1 (0.48) | BLMTSHRNFKB1SLC6A2SLC6A4 | |
| SCHEMBL11219189 | 0.78 | OPRM1 (0.48) | BLMTSHRNFKB1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334647-A | Reactive dyes, their preparation and their use | HUNTSMAN ADV MAT SWITZERLAND | 2015-02-04 | — | — | CN | disclosed |
| CN-103270071-B | Self-crosslinking polysiloxane-odified polyhydroxy polyurethane resin, resin material containing same, method for producing same, artificial leather comprising same, and thermoplastic polyolefin skin material comprising same | DAINICHISEIKA COLOR CHEM | 2014-11-26 | — | — | CN | disclosed |
| CN-102958978-B | Self-crosslinkable polyhydroxy polyurethane resin, process for production of the resin, and resinaceous material that contains the resin | DAINICHISEIKA COLOR CHEM | 2014-11-19 | — | — | CN | disclosed |
| CN-103270071-A | Self-crosslinking polysiloxane-odified polyhydroxy polyurethane resin, resin material containing same, method for producing same, artificial leather comprising same, and thermoplastic polyolefin skin material comprising same | DAINICHISEIKA COLOR CHEM | 2013-08-28 | — | — | CN | disclosed |
| CN-101541908-B | Moisture-curing hot-melt adhesive compound containing polyaldimine | SIKA TECHNOLOGY AG | 2013-05-22 | — | — | CN | disclosed |
| CN-102958978-A | Self-crosslinkable polyhydroxy polyurethane resin, resinaceous material that contains the resin, process for production of the resin, and imitation leather, surfacing material and weatherstrip material, using the resin | DAINICHISEIKA COLOR CHEM | 2013-03-06 | — | — | CN | disclosed |
| CN-100372532-C | Imidazolin-2-ylaminophenyl amides as IP antagonists. | HOFFMANN LA ROCHE (CH) | 2008-03-05 | — | — | CN | disclosed |
| US-7279498-B2 | Substituted aryl amides as IP antagonists | ROCHE PALO ALTO LLC (US) | 2007-10-09 | — | — | US | disclosed |
| CN-1303125-C | Aqueous polyurethane dispersion and method for making and using same | AIR PROD & CHEM (US) | 2007-03-07 | — | — | CN | disclosed |
| CN-1780617-A | Imidazolin-2-ylaminophenyl amides as IP antagonists. | HOFFMANN LA ROCHE (CH) | 2006-05-31 | — | — | CN | disclosed |
| US-6998414-B2 | Substituted arylamides as IP antagonists | ROCHE PALO ALTO LLC (US) | 2006-02-14 | — | — | US | disclosed |
| EP-1622611-A1 | IMIDAZOLIN-2-YLAMINOPHENYL AMIDES AS IP ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-02-08 | — | — | EP | disclosed |
| US-20060004075-A1 | Substituted aryl amides as IP antagonists | ROCHE PALO ALTO LLC | 2006-01-05 | — | — | US | disclosed |
| CN-1637035-A | Aqueous polyurethane dispersion and method for making and using same | AIR PROD & CHEM (US) | 2005-07-13 | — | — | CN | disclosed |
| WO-2004096213-A1 | IMIDAZOLIN-2-YLAMINOPHENYL AMIDES AS IP ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-11-11 | — | — | WO | disclosed |
| US-20040220247-A1 | Substituted arylamides as IP antagonists | ROCHE PALO ALTO LLC | 2004-11-04 | — | — | US | disclosed |
| US-4775419-A | Metal amine complexes for improving the bond strength properties of asphalt | MORTON THIOKOL, INC. (US) | 1988-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004075-A1 | Substituted aryl amides as IP antagonists | INSR, INSRR, GIPR | BLM 1870/4885TSHR 38/4885NFKB1 2491/4885 |
| US-20040220247-A1 | Substituted arylamides as IP antagonists | INSR, PTGER1, INSRR | BLM 2321/4885TSHR 144/4885NFKB1 3414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.