Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28870792 | 1.00 | XDH (0.53) | XDHBACE1MAPTTP53KDM4E | |
| SCHEMBL544419 | 0.87 | ABCG2 (0.53) | XDHKDM4EMAPK1ALDH1A1LMNA | |
| SCHEMBL544418 | 0.87 | ABCG2 (0.53) | XDHKDM4EMAPK1ALDH1A1LMNA | |
| SCHEMBL743608 | 0.82 | ALDH1A1 (0.57) | BACE1MAPTTP53KDM4EMAPK1 | |
| SCHEMBL9159172 | 0.81 | CDK4 (0.59) | XDHMAPTKDM4EMAPK1ALDH1A1 | |
| SCHEMBL9929133 | 0.80 | MAPT (0.55) | BACE1MAPTTP53KDM4EMAPK1 | |
| SCHEMBL31501089 | 0.78 | BACE1 (0.59) | BACE1MAPTTP53KDM4EMAPK1 | |
| SCHEMBL28431502 | 0.77 | CDK4 (0.50) | XDHMAPTKDM4EMAPK1ALDH1A1 | |
| SCHEMBL28431503 | 0.77 | CDK4 (0.50) | XDHMAPTKDM4EMAPK1ALDH1A1 | |
| SCHEMBL25192185 | 0.76 | MAPT (0.45) | MAPTALDH1A1LMNACYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092769-B | Chromene derivative and synthesis method and application thereof | 华东师范大学 | 2022-09-20 | — | — | CN | claimed |
| CN-110092769-B | Chromene derivative and synthesis method and application thereof | 华东师范大学 | 2022-09-20 | — | — | CN | disclosed |