Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28409048 | 0.98 | GPR119 (0.44) | GPR119ALDH1A1LMNAMAPK1L3MBTL1 | |
| SCHEMBL3844065 | 0.95 | GPR119 (0.41) | GPR119ALDH1A1LMNAMAPK1L3MBTL1 | |
| SCHEMBL7056630 | 0.78 | INPP5A (0.40) | GPR119ALDH1A1LMNAMAPK1L3MBTL1 | |
| SCHEMBL4121215 | 0.75 | GPR119 (0.42) | GPR119KMT2A | |
| SCHEMBL12226351 | 0.75 | SIGMAR1 (0.39) | ALDH1A1LMNAAPPKMT2A | |
| SCHEMBL355314 | 0.73 | SIGMAR1 (0.47) | APPKMT2A | |
| SCHEMBL2570161 | 0.73 | APP (0.38) | ALDH1A1LMNAHPGDAPPKMT2A | |
| SCHEMBL8322595 | 0.73 | SIGMAR1 (0.47) | APPKMT2A | |
| SCHEMBL20073870 | 0.73 | GPR119 (0.46) | GPR119ALDH1A1HPGDKMT2APKM | |
| SCHEMBL3105507 | 0.72 | APP (0.44) | ALDH1A1LMNAMAPK1HPGDAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233863-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2022-10-25 | — | — | CN | disclosed |