Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 13/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.57 |
| ▸ | PDE4A | P27815 | 11/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28870891 | 0.95 | PDE4B (0.64) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL6799815 | 0.86 | PDE4B (0.71) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL16544966 | 0.83 | PDE4B (0.67) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL7384113 | 0.83 | PDE4B (0.62) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL7443746 | 0.83 | PDE4D (0.61) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL563069 | 0.82 | CA12 (0.67) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL30555836 | 0.82 | CA12 (0.67) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7364684 | 0.82 | PDE4D (0.60) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL30009845 | 0.80 | PDE4B (0.80) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL1028427 | 0.80 | PDE4B (0.80) | PDE4BPDE4DPDE4APDE4CMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209848-B | Cyclopentane-containing cinnamamide derivative with neuroprotective activity and preparation method thereof | 中山大学 | 2022-10-25 | — | — | CN | disclosed |