Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 6/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2731878 | 0.86 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2TAAR1LMNA | |
| SCHEMBL29145671 | 0.85 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2TAAR1LMNA | |
| SCHEMBL4031932 | 0.81 | POLB (0.69) | NPC1RAB9ASMN1; SMN2TAAR1LMNA | |
| SCHEMBL863136 | 0.81 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2TAAR1LMNA | |
| SCHEMBL2653237 | 0.80 | RAB9A (0.76) | NPC1RAB9ASMN1; SMN2TAAR1LMNA | |
| SCHEMBL10928554 | 0.80 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2TAAR1LMNA | |
| SCHEMBL25572999 | 0.78 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2TAAR1LMNA | |
| SCHEMBL21493485 | 0.78 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2TAAR1LMNA | |
| SCHEMBL5251770 | 0.78 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2TAAR1LMNA | |
| SCHEMBL10932130 | 0.78 | HPGD (0.64) | NPC1RAB9ASMN1; SMN2TAAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222628-A | Compound for inhibiting apoptosis and preparation method thereof | 中国科学院上海有机化学研究所 | 2023-12-12 | — | — | CN | disclosed |
| CN-115246796-A | Compound for inhibiting programmed cell death and preparation method thereof | 中国科学院上海有机化学研究所 | 2022-10-28 | — | — | CN | disclosed |