Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22599745 | 0.86 | MAPT (0.59) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL28872876 | 0.83 | PKM (0.62) | MAPTALDH1A1GSK3BLMNARAB9A | |
| SCHEMBL5167787 | 0.81 | MAPT (0.52) | MAPTALDH1A1GSK3BLMNARAB9A | |
| SCHEMBL2684424 | 0.81 | SRD5A2 (0.62) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL8985359 | 0.80 | NPC1 (0.59) | MAPTALDH1A1GSK3BLMNARAB9A | |
| SCHEMBL668743 | 0.80 | NPC1 (0.63) | MAPTALDH1A1GSK3BRAB9ANPC1 | |
| SCHEMBL6751078 | 0.80 | MAPT (0.72) | MAPTALDH1A1GSK3BLMNARAB9A | |
| SCHEMBL199347 | 0.80 | CRHBP (0.62) | MAPTALDH1A1GSK3BRAB9ANPC1 | |
| SCHEMBL4319309 | 0.80 | CES2 (0.61) | MAPTALDH1A1GSK3BRAB9ANPC1 | |
| SCHEMBL13236074 | 0.79 | MAPT (0.53) | MAPTALDH1A1GSK3BRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705051-B | 2, 4, 5-trisubstituted oxazole and synthesis method thereof | 湖南城市学院 | 2022-09-23 | — | — | CN | disclosed |