Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | CSF1R | P07333 | 1/20 | 0.59 |
| ▸ | RET | P07949 | 1/20 | 0.59 |
| ▸ | MET | P08581 | 1/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.59 |
| ▸ | FLT3 | P36888 | 1/20 | 0.59 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.59 |
| ▸ | CDK8 | P49336 | 1/20 | 0.59 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.59 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.59 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.59 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000250 | 0.90 | CCR1 (0.54) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL26567788 | 0.89 | PDGFRB (0.50) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL2997318 | 0.88 | CCR1 (0.60) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL15040982 | 0.88 | AURKA (0.58) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL4404647 | 0.83 | CCR1 (0.64) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL25779883 | 0.82 | NPC1 (0.51) | FLT3NPC1ALDH1A3RXFP1RAB9A | |
| SCHEMBL12339169 | 0.82 | MEN1 (0.50) | NPC1ALDH1A3KDM1ACCR1CCR5 | |
| SCHEMBL2187794 | 0.82 | MEN1 (0.50) | NPC1ALDH1A3KDM1ACCR1CCR5 | |
| SCHEMBL10000248 | 0.81 | CCR1 (0.68) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL28241914 | 0.81 | NPC1 (0.50) | AURKAABL1NTRK1LCKCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003020-A | A kind of electroluminescent organic material and the preparation method and application thereof fluorene structured with spiral shell two | 北京燕化集联光电技术有限公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-109970578-A | A kind of organic compound and the preparation method and application thereof fluorene structured with 9,9 '-spiral shells two | 北京燕化集联光电技术有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-109970577-A | It is a kind of with the compound and the preparation method and application thereof fluorene structured containing methylspiro two | 北京燕化集联光电技术有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-109942440-A | A kind of OLED material and the preparation method and application thereof fluorene structured with spiral shell two | 北京燕化集联光电技术有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-109879763-A | A kind of organic light emission cavitation material and the preparation method and application thereof fluorene structured with spiral shell two | 北京燕化集联光电技术有限公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-109776396-A | A kind of organic compound and the preparation method and application thereof fluorene structured with spiral shell two | 北京燕化集联光电技术有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109776397-A | A kind of organic compound and the preparation method and application thereof fluorene structured with 9,9 '-spiral shells two | 北京燕化集联光电技术有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109776395-A | A kind of cavitation material and the preparation method and application thereof that fluorine-containing spiral shell two is fluorene structured | 北京燕化集联光电技术有限公司 | 2019-05-21 | — | — | CN | disclosed |