SCHEMBL2997318

SCHEMBL2997318

Cc1ccc(-c2ccc(F)cc2)nc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.60
CCR5 P51681 1/20 0.60
CCR8 P51685 1/20 0.60
HDAC6 Q9UBN7 1/20 0.60
AURKA O14965 1/20 0.58
ABL1 P00519 1/20 0.58
NTRK1 P04629 1/20 0.58
LCK P06239 1/20 0.58
CSF1R P07333 1/20 0.58
RET P07949 1/20 0.58
MET P08581 1/20 0.58
PDGFRB P09619 1/20 0.58
PIM1 P11309 1/20 0.58
PDGFRA P16234 1/20 0.58
FLT3 P36888 1/20 0.58
MAPK8 P45983 1/20 0.58
CDK8 P49336 1/20 0.58
MAP2K1 Q02750 1/20 0.58
MAP4K2 Q12851 1/20 0.58
ROCK1 Q13464 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17051514 0.89 CCR1 (0.75) CCR1CCR5CCR8HDAC6AURKA
SCHEMBL28873007 0.88 AURKA (0.59) CCR1CCR5CCR8HDAC6AURKA
SCHEMBL15040982 0.88 AURKA (0.58) CCR1CCR5CCR8HDAC6AURKA
SCHEMBL2477927 0.87 CCR1 (0.71) CCR1CCR5CCR8HDAC6AURKA
SCHEMBL10000248 0.85 CCR1 (0.68) CCR1CCR5CCR8HDAC6AURKA
SCHEMBL2480932 0.84 CYP3A4 (0.50) CCR1CCR5CCR8HDAC6AURKA
SCHEMBL17230040 0.83 CCR1 (0.46) CCR1CCR5CCR8HDAC6AURKA
SCHEMBL3771686 0.83 CYP3A4 (0.49) CCR1CCR5CCR8HDAC6AURKA
SCHEMBL17051522 0.83 CCR1 (0.65) CCR1CCR5CCR8HDAC6AURKA
SCHEMBL12846431 0.81 CCR1 (0.62) CCR1CCR5CCR8HDAC6AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11890604-B2 Composite catalyst for carbon dioxide reduction and method of fabricating of the same KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) 2024-02-06 US disclosed
US-20240002927-A1 METHODS FOR DETECTION OF NUCLEOTIDE MODIFICATION BLUECAT IP LIMITED (GB) 2024-01-04 US disclosed
US-20230416815-A1 METHOD FOR LABELING NUCLEIC ACID CAMBRIDGE ENTERPRISE LIMITED (GB) 2023-12-28 US disclosed
EP-4240869-A1 METHODS FOR DETECTION OF NUCLEOTIDE MODIFICATION Bluecat IP Limited (GB) 2023-09-13 EP disclosed
CN-116685694-A Method for detecting nucleotide modifications 蓝猫知识产权有限公司 2023-09-01 CN disclosed
EP-4211262-A1 METHOD FOR LABELING NUCLEIC ACID Cambridge Enterprise Limited (GB) 2023-07-19 EP disclosed
CN-116323603-A Method for labeling nucleic acids 剑桥实业有限公司 2023-06-23 CN disclosed
US-11390575-B2 Isomerisation reaction FIRMENICH SA (CH) 2022-07-19 US disclosed
WO-2022096751-A1 METHODS FOR DETECTION OF NUCLEOTIDE MODIFICATION BLUECAT IP LIMITED (GB) 2022-05-12 WO disclosed
WO-2022053718-A1 METHOD FOR LABELING NUCLEIC ACID CAMBRIDGE ENTERPRISE LIMITED (GB) 2022-03-17 WO disclosed
US-20100144046-A1 CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION BIO-RAD LABORATORIES, INC. (US) 2010-06-10 US disclosed
WO-2010052625-A1 PYRROLIDINES PFIZER LIMITED (GB) 2010-05-14 WO disclosed
US-20100120793-A1 Pyrrolidines PFIZER ANIMAL HEALTH UK 1 LIMITED (GB) 2010-05-13 US disclosed
EP-2155765-A1 BIPYRIDINE METAL COMPLEXES FOR USE AS LIGHT-EMITTING MATERIAL SOLVAY (BE) 2010-02-24 EP disclosed
WO-2009002423-A2 POLYCYCLIC GUANINE DERIVATIVES AND USE THEREOF SCHERING CORPORATION (US) 2008-12-31 WO disclosed
WO-2008148830-A1 BIPYRIDINE METAL COMPLEXES FOR USE AS LIGHT-EMITTING MATERIAL SOLVAY (BE) 2008-12-11 WO disclosed
US-7332232-B2 OLEDs utilizing multidentate ligand systems UNIVERSAL DISPLAY CORPORATION (US) 2008-02-19 US disclosed
US-7332232-B2 OLEDs utilizing multidentate ligand systems UNIVERSAL DISPLAY CORPORATION (US) 2008-02-19 US disclosed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 US disclosed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100120793-A1 Pyrrolidines PTGER2, PTGDR2, PTGES2 CCR1 2940/4885CCR5 2405/4885CCR8 3456/4885
US-20230416815-A1 METHOD FOR LABELING NUCLEIC ACID ALKBH1, ALKBH2, NT5C3B CCR1 4396/4885CCR5 2287/4885CCR8 3428/4885
US-20100144046-A1 CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION CAD, NCLN, CCL5 CCR1 230/4885CCR5 48/4885CCR8 250/4885
US-11390575-B2 Isomerisation reaction CYP3A4, CYP4A11, UGT1A10 CCR1 433/4885CCR5 555/4885CCR8 502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.