Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18921529 | 1.00 | DDB1 (0.36) | DDB1CRBNRIPK1JAK2JAK1 | |
| SCHEMBL29966468 | 1.00 | DDB1 (0.36) | DDB1CRBNRIPK1JAK2JAK1 | |
| SCHEMBL29967034 | 1.00 | DDB1 (0.36) | DDB1CRBNRIPK1JAK2JAK1 | |
| SCHEMBL29048248 | 0.87 | DGAT1 (0.39) | DDB1CRBNGPR119WNT3ARECQL | |
| SCHEMBL29966472 | 0.87 | DGAT1 (0.39) | DDB1CRBNGPR119WNT3ARECQL | |
| SCHEMBL18921328 | 0.87 | DGAT1 (0.39) | DDB1CRBNGPR119WNT3ARECQL | |
| SCHEMBL30547503 | 0.87 | DGAT1 (0.39) | DDB1CRBNGPR119WNT3ARECQL | |
| SCHEMBL25816413 | 0.86 | TSHR (0.37) | DDB1CRBNRIPK1 | |
| SCHEMBL28243189 | 0.85 | MGLL (0.35) | DDB1CRBNRIPK1GPR119WNT3A | |
| SCHEMBL29966499 | 0.85 | MGLL (0.35) | DDB1CRBNRIPK1GPR119WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602809-B | Isoxazolidine derived inhibitors of receptor interacting protein kinase 1(RIPK 1) | 戴纳立制药公司 | 2022-09-30 | — | — | CN | disclosed |