Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30036241 | 1.00 | ENPEP (0.49) | ENPEPALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL28873191 | 0.90 | HDAC8 (0.40) | ENPEPALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL15630694 | 0.83 | CTSK (0.43) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27936273 | 0.83 | CTSK (0.43) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL20223064 | 0.83 | CTSK (0.43) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7074842 | 0.81 | S1PR2 (0.41) | ALDH1A1GRIK1SLC1A2SLC1A1GRIK2 | |
| SCHEMBL27517907 | 0.81 | S1PR2 (0.41) | ALDH1A1GRIK1SLC1A2SLC1A1GRIK2 | |
| SCHEMBL7824510 | 0.80 | CYP2D6 (0.40) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10825310 | 0.80 | S1PR2 (0.44) | ALDH1A1GRIK1SLC1A2SLC1A1GRIK2 | |
| SCHEMBL31301962 | 0.80 | CYP2D6 (0.44) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177780-B | Pyrimidine compounds containing acidic groups | 阿普罗斯治疗公司 | 2022-11-01 | — | — | CN | disclosed |