Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 6/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074842 | 1.00 | S1PR2 (0.41) | S1PR2S1PR1S1PR3S1PR4GRIK1 | |
| SCHEMBL10825310 | 0.98 | S1PR2 (0.44) | S1PR2S1PR1S1PR3S1PR4GRIK1 | |
| SCHEMBL15630694 | 0.95 | CTSK (0.43) | S1PR2S1PR1SLC1A2SLC1A1CTSK | |
| SCHEMBL27936273 | 0.95 | CTSK (0.43) | S1PR2S1PR1SLC1A2SLC1A1CTSK | |
| SCHEMBL20223064 | 0.95 | CTSK (0.43) | S1PR2S1PR1SLC1A2SLC1A1CTSK | |
| SCHEMBL28652468 | 0.87 | CYP2D6 (0.39) | S1PR2S1PR1GRIK1GRIK2SLC1A2 | |
| SCHEMBL28873191 | 0.84 | HDAC8 (0.40) | CTSKALDH1A1CTSS | |
| SCHEMBL31138115 | 0.83 | ALDH1A1 (0.51) | S1PR2S1PR1S1PR3S1PR4GRIK1 | |
| SCHEMBL28873192 | 0.81 | ENPEP (0.49) | GRIK1GRIK2SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL30036241 | 0.81 | ENPEP (0.49) | GRIK1GRIK2SLC1A2SLC1A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1330638-C | Substituted imidazolidine derivatives, their prepn., their use and pharmaceutical prepn. comprising them | HOECHST MARION ROUSSEL DE GMBH (DE) | 2007-08-08 | — | — | CN | disclosed |
| CN-1225360-A | Substituted imidazolidine derivatives, their prepn., their use and pharmaceutical prepn. comprising them | HOECHST MARION ROUSSEL DE GMBH (DE) | 1999-08-11 | — | — | CN | disclosed |