SCHEMBL28873233

SCHEMBL28873233

N#CC(N)c1ccccc1COc1cccc2c1OCO2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PLAU P00749 1/20 0.36
HTR2A P28223 1/20 0.35
ALDH1A1 P00352 4/20 0.33
SGMS2 Q8NHU3 3/20 0.33
LMNA P02545 2/20 0.33
HTR1A P08908 1/20 0.33
POLB P06746 1/20 0.33
TACR1 P25103 1/20 0.33
HPGD P15428 2/20 0.33
TSHR P16473 2/20 0.33
MAPK1 P28482 2/20 0.33
HSD17B10 Q99714 2/20 0.33
ALOX15 P16050 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28295914 0.80 KMT2A (0.40) KMT2ATDP1L3MBTL1PLAUHTR2A
SCHEMBL28294082 0.75 FOLH1 (0.41) KMT2ATDP1L3MBTL1ALDH1A1MEN1
SCHEMBL10522223 0.73 MAOB (0.53) KMT2ATDP1L3MBTL1ALDH1A1LMNA
SCHEMBL28295913 0.71 TP53 (0.57) KMT2ATDP1L3MBTL1ALDH1A1MEN1
SCHEMBL13534203 0.71 AOC3 (0.54) KMT2AALDH1A1LMNAHTR1APOLB
SCHEMBL4309152 0.68 MTNR1A (0.48) KMT2ATDP1L3MBTL1ALDH1A1LMNA
SCHEMBL28325500 0.68 MTNR1A (0.44) KMT2ATDP1L3MBTL1ALDH1A1POLB
SCHEMBL11039239 0.68 HTR1A (0.41) KMT2ATDP1L3MBTL1HTR2AALDH1A1
SCHEMBL25335293 0.67 HTR1B (0.46) KMT2ATDP1L3MBTL1ALDH1A1HTR1A
SCHEMBL17274865 0.67 MAPT (0.44) KMT2ATDP1L3MBTL1HTR2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109651190-A A kind of synthetic method of kresoxim-methyl 京博农化科技有限公司 2019-04-19 CN disclosed