Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.67 |
| ▸ | CCND1 | P24385 | 1/20 | 0.67 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 2/20 | 0.51 |
| ▸ | KIF11 | P52732 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1181826 | 0.91 | CDK4 (0.79) | CDK4CCND1AHRPARP1KIF11 | |
| SCHEMBL30235013 | 0.91 | CDK4 (0.79) | CDK4CCND1AHRPARP1KIF11 | |
| Water SCHEMBL411737 | 0.89 | CDK4 (0.76) | CDK4CCND1AHRPARP1KIF11 | |
| Hydrochloric Acid SCHEMBL6432050 | 0.89 | CDK4 (0.76) | CDK4CCND1AHRPARP1KIF11 | |
| Hydrochloric Acid SCHEMBL30404107 | 0.89 | CDK4 (0.76) | CDK4CCND1AHRPARP1KIF11 | |
| Carbazole SCHEMBL28081524 | 0.84 | ALDH1A1 (0.70) | AHRPARP1KIF11ALDH1A1GPR3 | |
| SCHEMBL6325907 | 0.84 | CDK4 (0.69) | CDK4CCND1AHRPARP1KIF11 | |
| SCHEMBL29683901 | 0.80 | KIF11 (0.67) | CDK4CCND1AHRPARP1KIF11 | |
| SCHEMBL64877 | 0.80 | KIF11 (0.67) | CDK4CCND1AHRPARP1KIF11 | |
| SCHEMBL6689351 | 0.80 | CDK4 (1.00) | CDK4CCND1AHRPARP1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851550-A | 7- aminocarbazole sulfamide derivative and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2019-06-07 | — | — | CN | claimed |
| CN-109851550-A | 7- aminocarbazole sulfamide derivative and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2019-06-07 | — | — | CN | disclosed |
| CN-109851550-A | 7- aminocarbazole sulfamide derivative and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2019-06-07 | — | — | CN | disclosed |
| CN-109851550-A | 7- aminocarbazole sulfamide derivative and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2019-06-07 | — | — | CN | disclosed |