SCHEMBL28873751

SCHEMBL28873751

CC(C)(C)OC(=O)NCC(=O)ON1C(=O)C=CC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 2/20 0.41
EPHX2 P34913 1/20 0.41
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40
ALDH1A1 P00352 2/20 0.40
TSHR P16473 2/20 0.40
TDP1 Q9NUW8 1/20 0.38
NFKB1 P19838 4/20 0.38
NFKB2 Q00653 4/20 0.38
RELA Q04206 4/20 0.38
SIGMAR1 Q99720 1/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
GAA P10253 2/20 0.37
KDM4E B2RXH2 2/20 0.37
LMNA P02545 2/20 0.37
GLA P06280 1/20 0.37
CASP1 P29466 1/20 0.37
RAB9A P51151 1/20 0.37
CASP7 P55210 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1565316 0.87 ALDH1A1 (0.46) AKT1MAPTHPGDALDH1A1TSHR
SCHEMBL242270 0.81 L3MBTL1 (0.41) EPHX2MAPTHPGDALDH1A1TSHR
SCHEMBL21848450 0.80 MALT1 (0.47) EPHX2HPGDALDH1A1SIGMAR1KDM4E
SCHEMBL1564922 0.79 CYP2D6 (0.42) AKT1NFKB1NFKB2RELA
SCHEMBL10136052 0.77 NPFFR1 (0.39) EPHX2MAPTHPGDALDH1A1TSHR
SCHEMBL10046524 0.77 NPFFR1 (0.39) EPHX2MAPTHPGDALDH1A1TSHR
SCHEMBL19901583 0.75 AKT1 (0.43) AKT1EPHX2MAPTHPGDALDH1A1
SCHEMBL905713 0.74 ELANE (0.38) AKT1MAPTHPGDALDH1A1TDP1
SCHEMBL27389263 0.74 GSK3A (0.34) HPGDALDH1A1
SCHEMBL22915492 0.74 AKT1 (0.54) AKT1ALDH1A1TDP1SIGMAR1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109890822-A INHIBITORS OF CELLULAR METABOLIC PROCESSES 安吉奥斯医药品有限公司 2019-06-14 CN disclosed