Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.43 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.35 |
| ▸ | RELA | Q04206 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347403 | 0.86 | AKT1 (0.53) | AKT1NPFFR1NPFFR2ALDH1A1SIGMAR1 | |
| SCHEMBL22915492 | 0.84 | AKT1 (0.54) | AKT1NPFFR1NPFFR2ALDH1A1SIGMAR1 | |
| SCHEMBL29173773 | 0.80 | AKT1 (0.45) | AKT1NPFFR1NPFFR2ALDH1A1SIGMAR1 | |
| SCHEMBL19901567 | 0.79 | MGLL (0.36) | ALDH1A1MAPTHPGDBLMGMNN | |
| SCHEMBL19695710 | 0.78 | MEN1 (0.48) | AKT1TDP1BRD4MAOAMAOB | |
| SCHEMBL19901553 | 0.77 | MGLL (0.39) | ALDH1A1MAPTHPGDBLMGMNN | |
| SCHEMBL998261 | 0.76 | AKT1 (0.59) | AKT1ALDH1A1TDP1MAOAMAOB | |
| SCHEMBL17527850 | 0.75 | AKT1 (0.49) | AKT1ALDH1A1TDP1MAOAMAOB | |
| SCHEMBL19901555 | 0.75 | TERT (0.41) | ALDH1A1MAPTHPGDBLMGMNN | |
| SCHEMBL28873751 | 0.75 | AKT1 (0.41) | AKT1EPHX2ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961435-B1 | CONJUGATES COMPRISING CELL-BINDING AGENTS AND CYTOTOXIC AGENTS | IMMUNOGEN INC (US) | 2019-05-01 | — | — | EP | disclosed |
| US-9901647-B2 | Conjugates comprising cell-binding agents and cytotoxic agents | IMMUNOGEN, INC. (US) | 2018-02-27 | — | — | US | disclosed |