Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2062113 | 0.75 | PIN1 (0.40) | POLBCASP6PIN1ALDH1A1GAA | |
| SCHEMBL2062610 | 0.73 | PIN1 (0.47) | POLBCASP6PIN1ALDH1A1GAA | |
| SCHEMBL29596360 | 0.70 | PIN1 (0.64) | POLBCASP6PIN1ALDH1A1GAA | |
| SCHEMBL22895754 | 0.70 | PIN1 (0.64) | POLBCASP6PIN1ALDH1A1GAA | |
| SCHEMBL1981633 | 0.70 | ALDH1A1 (0.46) | POLBCASP6PIN1ALDH1A1GAA | |
| SCHEMBL9193480 | 0.69 | CTSC (0.38) | POLBCASP6PIN1 | |
| SCHEMBL24392929 | 0.68 | PIN1 (0.43) | POLBCASP6PIN1ALDH1A1GAA | |
| SCHEMBL3813480 | 0.68 | KCNH2 (0.44) | POLBPIN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30584579 | 0.68 | PIN1 (0.43) | POLBCASP6PIN1ALDH1A1GAA | |
| SCHEMBL16618084 | 0.68 | FEN1 (0.44) | POLBCASP6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260105-B | Aromatic heterocarbamic acid compound and preparation method and application thereof | 启东东岳药业有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-115260105-A | Aromatic heterocyclic carbamic acid compound and preparation method and application thereof | 启东东岳药业有限公司 | 2022-11-01 | — | — | CN | disclosed |