Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 10/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | XPO1 | O14980 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | ATF1 | P18846 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191410 | 0.82 | PIN1 (0.33) | PIN1POLBCASP6MKNK1MKNK2 | |
| SCHEMBL22895466 | 0.77 | NUDT1 (0.43) | PIN1POLBCASP6MKNK1MKNK2 | |
| SCHEMBL1981633 | 0.72 | ALDH1A1 (0.46) | PIN1POLBCASP6NUDT1 | |
| SCHEMBL9196363 | 0.72 | ALDH1A1 (0.33) | — | |
| SCHEMBL25353609 | 0.70 | SLC7A5 (0.41) | CTSC | |
| SCHEMBL5021094 | 0.69 | NUDT1 (0.39) | PIN1MKNK1MKNK2NUDT1NFKB1 | |
| SCHEMBL29596360 | 0.69 | PIN1 (0.64) | PIN1POLBCASP6 | |
| SCHEMBL22895754 | 0.69 | PIN1 (0.64) | PIN1POLBCASP6 | |
| SCHEMBL5021107 | 0.69 | NUDT1 (0.33) | PIN1POLBCASP6MKNK1MKNK2 | |
| SCHEMBL28874643 | 0.69 | POLB (0.39) | PIN1POLBCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445644-B1 | Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation | BASF AG (DE) | 1995-05-24 | — | — | EP | disclosed |
| US-5237063-A | TRIFLUORO- AND CHLORODIFLUOROMETHOXYPYRIMIDINES AND THE PREPARATION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1993-08-17 | — | — | US | disclosed |
| EP-0445644-A1 | Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |