Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28308895 | 0.76 | NFE2L2 (0.36) | MAOBCYP1A1CYP1B1NFE2L2PTPN1 | |
| SCHEMBL16400448 | 0.76 | MAOB (0.46) | MAOBCYP1A1CYP1B1NFE2L2PTPN1 | |
| SCHEMBL16400445 | 0.76 | MAOB (0.46) | MAOBCYP1A1CYP1B1NFE2L2PTPN1 | |
| SCHEMBL28780257 | 0.74 | NFE2L2 (0.45) | MAOBCYP1A1CYP1B1NFE2L2PTPN1 | |
| SCHEMBL18002139 | 0.73 | NFE2L2 (0.47) | MAOBCYP1A1CYP1B1NFE2L2TP53 | |
| SCHEMBL138245 | 0.71 | TAS2R14 (0.39) | CYP1A1CYP1B1MAPT | |
| SCHEMBL31088711 | 0.70 | ERN1 (0.33) | MAPT | |
| SCHEMBL1355609 | 0.70 | ERN1 (0.33) | MAPT | |
| SCHEMBL1570518 | 0.68 | ALDH1A1 (0.39) | MAPT | |
| SCHEMBL153259 | 0.68 | BACE1 (0.42) | MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109956898-A | Immunomodulator and its preparation method and purposes pharmaceutically | 上海海雁医药科技有限公司 | 2019-07-02 | — | — | CN | disclosed |