Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692996 | 0.83 | ALDH1A1 (0.48) | ALDH1A1POLBTDP1L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL11842627 | 0.81 | ALDH1A1 (0.47) | ALDH1A1POLBTDP1L3MBTL1LMNA | |
| SCHEMBL9456596 | 0.80 | KMT2A (0.50) | ALDH1A1POLBL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL12550518 | 0.80 | POLB (0.50) | ALDH1A1POLBTDP1L3MBTL1LMNA | |
| SCHEMBL11744074 | 0.80 | ALDH1A1 (0.43) | ALDH1A1POLBTDP1L3MBTL1LMNA | |
| SCHEMBL28220404 | 0.79 | MAPT (0.42) | MAPTSMN1; SMN2GPBAR1KMT2AKDM4E | |
| SCHEMBL8986913 | 0.78 | ALDH1A1 (0.48) | ALDH1A1POLBTDP1L3MBTL1LMNA | |
| SCHEMBL2095575 | 0.78 | ALDH1A1 (0.48) | ALDH1A1POLBTDP1L3MBTL1LMNA | |
| SCHEMBL198522 | 0.78 | FSCN1 (0.55) | ALDH1A1POLBTDP1LMNACHRNB2 | |
| SCHEMBL10942532 | 0.77 | ALDH1A1 (0.47) | ALDH1A1POLBTDP1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107987017-B | - 2 (1H)-quinolinones compound of a kind of 3,4-dihydro and the preparation method and application thereof | 绍兴文理学院 | 2019-07-12 | — | — | CN | disclosed |