Pyridine

Pyridine

SCHEMBL28875342

c1ccc(-c2cccnn2)cc1.c1ccncc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.47
HDAC4 P56524 2/20 0.45
DHODH Q02127 1/20 0.45
NOTUM Q6P988 1/20 0.44
GABRA1 P14867 2/20 0.44
GABRG2 P18507 2/20 0.44
GABRB3 P28472 2/20 0.44
GABRA5 P31644 2/20 0.44
GABRA3 P34903 2/20 0.44
RAB9A P51151 5/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
CYP19A1 P11511 1/20 0.40
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 3/20 0.40
NPC1 O15118 3/20 0.39
ATAD2 Q6PL18 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
AR P10275 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL121970 0.91 RAB9A (0.50) CYP2A6HDAC4DHODHNOTUMGABRA1
SCHEMBL29959678 0.91 RAB9A (0.50) CYP2A6HDAC4DHODHNOTUMGABRA1
Hydrochloric Acid SCHEMBL28994315 0.89 HDAC4 (0.49) CYP2A6HDAC4DHODHNOTUMGABRA1
SCHEMBL28485342 0.89 HDAC4 (0.49) CYP2A6HDAC4DHODHNOTUMGABRA1
Water SCHEMBL11877808 0.89 HDAC4 (0.49) CYP2A6HDAC4DHODHNOTUMGABRA1
Hydrochloric Acid SCHEMBL9513928 0.89 HDAC4 (0.49) CYP2A6HDAC4DHODHNOTUMGABRA1
SCHEMBL13458062 0.87 GABRA1 (0.52) HDAC4DHODHNOTUMGABRA1GABRG2
SCHEMBL1456246 0.85 MAPT (0.46) HDAC4DHODHNOTUMGABRA1GABRG2
SCHEMBL4701329 0.81 CYP2A6 (0.59) CYP2A6RAB9ACYP19A1ALDH1A1KDM4E
Ether SCHEMBL11877801 0.77 RAB9A (0.46) HDAC4DHODHGABRA1GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109970806-A A kind of organic metal complex of iridium, preparation method and its application in OLED 江苏三月光电科技有限公司 2019-07-05 CN disclosed