SCHEMBL28485342

SCHEMBL28485342

[KH].c1ccc(-c2cccnn2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 2/20 0.49
DHODH Q02127 1/20 0.49
GABRA1 P14867 2/20 0.48
GABRG2 P18507 2/20 0.48
GABRB3 P28472 2/20 0.48
GABRA5 P31644 2/20 0.48
GABRA3 P34903 2/20 0.48
RAB9A P51151 4/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
NPC1 O15118 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
USP2 O75604 1/20 0.41
TP53 P04637 1/20 0.41
PKM P14618 1/20 0.41
ASIC3 Q9UHC3 2/20 0.40
MAPK1 P28482 1/20 0.40
NOTUM Q6P988 1/20 0.39
GPR84 Q9NQS5 2/20 0.38
CYP2A6 P11509 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29959678 0.98 RAB9A (0.50) HDAC4DHODHGABRA1GABRG2GABRB3
SCHEMBL121970 0.98 RAB9A (0.50) HDAC4DHODHGABRA1GABRG2GABRB3
Hydrochloric Acid SCHEMBL9513928 0.95 HDAC4 (0.49) HDAC4DHODHGABRA1GABRG2GABRB3
Water SCHEMBL11877808 0.95 HDAC4 (0.49) HDAC4DHODHGABRA1GABRG2GABRB3
Hydrochloric Acid SCHEMBL28994315 0.95 HDAC4 (0.49) HDAC4DHODHGABRA1GABRG2GABRB3
SCHEMBL13458062 0.93 GABRA1 (0.52) HDAC4DHODHGABRA1GABRG2GABRB3
Pyridine SCHEMBL28875342 0.89 CYP2A6 (0.47) HDAC4DHODHGABRA1GABRG2GABRB3
Ether SCHEMBL11877801 0.82 RAB9A (0.46) HDAC4DHODHGABRA1GABRG2GABRB3
SCHEMBL20427626 0.82 HPGDS (0.50) HDAC4DHODHGABRA1GABRG2GABRB3
SCHEMBL1456246 0.81 MAPT (0.46) HDAC4DHODHGABRA1GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116250545-B Bacillus amyloliquefaciens FCC1256 compositions and methods of controlling plant pathogens FMC公司 2025-05-09 CN disclosed
CN-116250545-A Bacillus amyloliquefaciens FCC1256 compositions and methods of controlling plant pathogens FMC公司 2023-06-13 CN disclosed
CN-114617136-A Microbial compositions and methods of use for promoting plant growth and treating plant diseases FMC有限公司 2022-06-14 CN disclosed
CN-107960103-B Microbial compositions and methods of use for promoting plant growth and treating plant diseases FMC有限公司 2021-12-03 CN disclosed
CN-113271780-A Bacillus amyloliquefaciens FCC1256 composition and method for controlling plant pathogens FMC公司 2021-08-17 CN disclosed
CN-106455574-B Foam formulations and emulsifiable concentrates FMC有限公司 2020-12-01 CN disclosed