Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 14/20 | 0.64 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.54 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.54 |
| ▸ | KIF11 | P52732 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27639783 | 0.79 | KIF11 (0.51) | KIF11LMNACHRM2CYP2D6CHRM1 | |
| SCHEMBL28875440 | 0.78 | KCNN4 (0.72) | KCNN4KCNE1KCNQ1KIF11MAPT | |
| Senicapoc SCHEMBL1443805 | 0.78 | KCNN4 (1.00) | KCNN4KCNE1KCNQ1KIF11MAPT | |
| SCHEMBL2337394 | 0.78 | KCNN4 (1.00) | KCNN4KCNE1KCNQ1KIF11MAPT | |
| SCHEMBL5432726 | 0.77 | KCNN4 (0.57) | KCNN4KCNE1KCNQ1KIF11MAPT | |
| SCHEMBL637563 | 0.75 | CYP1A2 (0.46) | KIF11LMNACHRM2CYP2D6CHRM1 | |
| SCHEMBL5056595 | 0.75 | KCNN4 (0.68) | KCNN4KCNE1KCNQ1KIF11MAPT | |
| SCHEMBL28151671 | 0.75 | KCNN4 (0.68) | KCNN4KCNE1KCNQ1KIF11MAPT | |
| SCHEMBL27361319 | 0.75 | KCNN4 (0.53) | KCNN4KCNE1KCNQ1KIF11CHRM2 | |
| SCHEMBL3432388 | 0.75 | KCNN4 (0.53) | KCNN4KCNE1KCNQ1KIF11CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101790374-A | Use of kncq potassium channel openers for reducing symptoms of or treating disorders or conditions wherein the dopaminergic system is disrupted | LUNDBECK & CO AS H | 2010-07-28 | — | — | CN | claimed |
| CN-1761464-A | Substituted p-diaminobenzene derivatives | LUNDBECK & CO AS H (DK) | 2006-04-19 | — | — | CN | claimed |
| CN-101378742-B | Use of KCNQ-openers for the preparation of a pharmaceutical composition for the treatment of schizophrenia | LUNDBECK & CO AS H | 2013-07-10 | — | — | CN | disclosed |
| CN-101790374-A | Use of kncq potassium channel openers for reducing symptoms of or treating disorders or conditions wherein the dopaminergic system is disrupted | LUNDBECK & CO AS H | 2010-07-28 | — | — | CN | disclosed |
| CN-1761464-A | Substituted p-diaminobenzene derivatives | LUNDBECK & CO AS H (DK) | 2006-04-19 | — | — | CN | disclosed |