Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28098320 | 0.74 | ADH1C (0.47) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL27868845 | 0.74 | ADH1C (0.47) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL28875541 | 0.71 | DNM1 (0.42) | DNM1NPC1JAK2RAB9APAX8 | |
| SCHEMBL8944529 | 0.70 | ADH1A (0.43) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL28684578 | 0.70 | ADH1A (0.43) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL11573150 | 0.69 | DNM1 (0.32) | DNM1 | |
| SCHEMBL4724456 | 0.66 | TDP1 (0.31) | — | |
| SCHEMBL97181 | 0.65 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL2361603 | 0.65 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL4724562 | 0.64 | DNM1 (0.33) | DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194396-B1 | ANTIALLERGENS; ANTIINFLAMMATION AGENTS; AUTOIMMUNE DISEASE; ANTISHOCK AGENTS; ANALGESICS; E.G., A 4 OR 7-PHENYLALKYLENE-OXYBENZIMIDAZOLE UNSUBSTITUTED OR SUBSTITUTED IN THE 1,2,3-POSITION WITH AN OXY, AMINO AND/OR THIO GROUP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-02-27 | — | — | US | claimed |