SCHEMBL28875792

SCHEMBL28875792

CCCCCCCN(C=O)C(C)C(O)C(=O)NCC1CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.39
FAAH O00519 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH4 P08319 1/20 0.38
TP53 P04637 1/20 0.34
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31
KMT2A Q03164 2/20 0.31
CNR1 P21554 2/20 0.31
CNR2 P34972 2/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19974882 0.79 KMT2A (0.38) KMT2ATDP1
SCHEMBL19975400 0.78 SMN1; SMN2 (0.40) METAP2ADH1CADH1AADH4KMT2A
SCHEMBL19974838 0.78 SMN1; SMN2 (0.40) METAP2ADH1CADH1AADH4KMT2A
SCHEMBL19974757 0.74 SMN1; SMN2 (0.42) KMT2AALDH1A1CYP1A2CYP2D6CYP2C9
SCHEMBL19974955 0.73 EPHX1 (0.33) KMT2AALDH1A1
SCHEMBL19975043 0.72 SMN1; SMN2 (0.38) METAP2KMT2AALDH1A1CYP2D6TDP1
SCHEMBL19975307 0.72 CTSD (0.34) KMT2ACNR1CNR2ALDH1A1
SCHEMBL19975527 0.71 ADH1C (0.46) METAP2ADH1CADH1AADH4KMT2A
SCHEMBL21176329 0.71 KMT2A (0.33) KMT2AALDH1A1TDP1
SCHEMBL21176382 0.71 CTSD (0.33) KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110062753-A Antiviral compounds 哈普洛根有限责任公司 2019-07-26 CN disclosed