Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.30 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid Methyl Ester SCHEMBL28112146 | 0.80 | ACHE (0.65) | ACHEALDH1A1TSHRLMNAGAA | |
| Naphthalene SCHEMBL28039997 | 0.76 | CYP1A2 (0.42) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL27329631 | 0.76 | ACHE (0.71) | ACHEALDH1A1TSHRGAANFE2L2 | |
| Formamide SCHEMBL7850207 | 0.76 | ACHE (0.71) | ACHEALDH1A1TSHRGAACYP3A4 | |
| Formic Acid SCHEMBL27295959 | 0.76 | ACHE (0.71) | ACHEALDH1A1TSHRGAAHTT | |
| Carbon Monoxide SCHEMBL5657042 | 0.75 | ACHE (0.79) | ACHEALDH1A1TSHRLMNAGAA | |
| SCHEMBL29488781 | 0.74 | — | — | |
| SCHEMBL11837 | 0.74 | — | — | |
| SCHEMBL28557764 | 0.73 | ACHE (0.83) | ACHEALDH1A1TSHRLMNAGAA | |
| Methoxymethane SCHEMBL27488985 | 0.73 | ACHE (0.83) | ACHEALDH1A1TSHRLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110099912-A | Antiviral tenofovir aliphatic ester prodrug | 默沙东公司 | 2019-08-06 | — | — | CN | disclosed |