Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 17/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 13/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29814571 | 0.85 | ADORA2B (0.48) | ADORA2BADORA2AADORA1HPGDGSK3A | |
| SCHEMBL23089063 | 0.85 | ADORA2B (0.48) | ADORA2BADORA2AADORA1HPGDGSK3A | |
| SCHEMBL23089798 | 0.81 | ADORA2B (0.53) | ADORA2BADORA2AADORA1HPGDGSK3A | |
| SCHEMBL29736565 | 0.77 | ADORA2B (0.44) | ADORA2BADORA2AADORA1HPGDGSK3A | |
| SCHEMBL23089682 | 0.77 | ADORA2B (0.44) | ADORA2BADORA2AADORA1HPGDGSK3A | |
| SCHEMBL23089598 | 0.76 | ADORA2B (0.41) | ADORA2BADORA2AADORA1HPGDGSK3A | |
| SCHEMBL29239372 | 0.76 | ADORA2B (0.40) | ADORA2BADORA2AADORA1HPGDGSK3A | |
| SCHEMBL23089599 | 0.76 | ADORA2B (0.40) | ADORA2BADORA2AADORA1HPGDGSK3A | |
| SCHEMBL29239375 | 0.76 | ADORA2B (0.40) | ADORA2BADORA2AADORA1HPGDGSK3A | |
| SCHEMBL30173075 | 0.76 | ADORA2B (0.40) | ADORA2BADORA2AADORA1HPGDGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945366-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2022-08-26 | — | — | CN | disclosed |