SCHEMBL29239372 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	ADORA2B	P29275	11/20	0.40

▸	ADORA2A	P29274	9/20	0.40

▸	ADORA1	P30542	7/20	0.40

▸	ABL1	P00519	1/20	0.40

▸	GSK3B	P49841	3/20	0.39

▸	GSK3A	P49840	1/20	0.39

▸	ADORA3	P0DMS8	3/20	0.39

▸	HPGD	P15428	1/20	0.38

▸	PIK3C3	Q8NEB9	1/20	0.38

▸	HTR1A	P08908	2/20	0.37

▸	HTR1D	P28221	2/20	0.37

▸	HTR1B	P28222	2/20	0.37

▸	HTR1F	P30939	2/20	0.37

▸	RXFP1	Q9HBX9	1/20	0.36

▸	L3MBTL1	Q9Y468	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29239375	1.00	ADORA2B (0.40)	ADORA2BADORA2AADORA1ABL1GSK3B
SCHEMBL30173075	1.00	ADORA2B (0.40)	ADORA2BADORA2AADORA1ABL1GSK3B
SCHEMBL29239398	0.78	ADORA2B (0.46)	ADORA2BADORA2AADORA1ABL1GSK3B
SCHEMBL24992530	0.78	ADORA2B (0.46)	ADORA2BADORA2AADORA1ABL1GSK3B
SCHEMBL30173072	0.78	ADORA2B (0.46)	ADORA2BADORA2AADORA1ABL1GSK3B
SCHEMBL29814571	0.76	ADORA2B (0.48)	ADORA2BADORA2AADORA1GSK3BGSK3A
SCHEMBL23089063	0.76	ADORA2B (0.48)	ADORA2BADORA2AADORA1GSK3BGSK3A
SCHEMBL28876487	0.76	ADORA2B (0.48)	ADORA2BADORA2AADORA1GSK3BGSK3A
SCHEMBL23089798	0.74	ADORA2B (0.53)	ADORA2BADORA2AADORA1GSK3BGSK3A
SCHEMBL24992531	0.73	HTR1A (0.41)	ABL1HPGDHTR1AHTR1DHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-117915912-A	HPK1 antagonists and uses thereof	林伯士萨顿公司	2024-04-19	—	—	CN	disclosed