Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947822 | 0.85 | ABCC8 (0.44) | KDM4EABCC8KCNJ11GAAALOX5AP | |
| SCHEMBL29350079 | 0.82 | KDM4E (0.35) | KDM4ETDP1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28877273 | 0.81 | ABCC8 (0.35) | ABCC8KCNJ11ALOX5APFEN1 | |
| SCHEMBL29350969 | 0.81 | KDM4E (0.36) | KDM4ETDP1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28877271 | 0.80 | ADORA2A (0.42) | TDP1KMT2AMEN1ABCC8KCNJ11 | |
| SCHEMBL29349663 | 0.80 | KDM4E (0.35) | KDM4ETDP1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28877261 | 0.79 | PDE3B (0.40) | ABCC8KCNJ11ALOX5APFEN1 | |
| SCHEMBL28020018 | 0.78 | ERN1 (0.41) | KDM4ETDP1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29947834 | 0.78 | RPS6KB2 (0.43) | KDM4ETDP1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28877299 | 0.76 | SMN1; SMN2 (0.37) | KDM4ETDP1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260245-A | Iridium metal complex, application thereof and organic electroluminescent device | 清华大学 | 2022-11-01 | — | — | CN | disclosed |