Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.45 |
| ▸ | ITGAL | P20701 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480234 | 1.00 | HDAC1 (0.46) | HDAC1HDAC8ITGB2ICAM1ITGAL | |
| SCHEMBL7483535 | 0.87 | ITGB2 (0.51) | ITGB2ICAM1ITGALKMT2AGAA | |
| SCHEMBL7483528 | 0.87 | ITGB2 (0.51) | ITGB2ICAM1ITGALKMT2AGAA | |
| SCHEMBL7480451 | 0.81 | HSP90AA1 (0.49) | KMT2AALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL7480459 | 0.81 | HSP90AA1 (0.49) | KMT2AALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL7480813 | 0.78 | MMP1 (0.55) | HDAC1KMT2AALDH1A1RAB9AMEN1 | |
| SCHEMBL7480810 | 0.78 | MMP1 (0.55) | HDAC1KMT2AALDH1A1RAB9AMEN1 | |
| SCHEMBL7835345 | 0.78 | MMP1 (0.52) | HDAC1HDAC8KMT2AALDH1A1RAB9A | |
| SCHEMBL7481651 | 0.77 | ALDH1A1 (0.54) | HDAC1ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL7481659 | 0.77 | ALDH1A1 (0.54) | HDAC1ITGB2ICAM1ITGALKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064273-B1 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | UPJOHN CO (US) | 2002-12-18 | — | — | EP | claimed |
| US-6150385-A | VIRICIDE WITH ACTIVITY AGAINST CYTOMEGALO VIRUS (CMV), HERPES VIRUS INCLUDING VARICELLA ZOSTER VIRUS, THE EPSTEIN-BARR VIRUS, THE HERPES SIMPLEX VIRUS, AND THE HUMAN HERPES VIRUS TYPE 8 (HHV-8) | PHARMACIA & UPJOHN COMPANY (US) | 2000-11-21 | — | — | US | claimed |
| EP-1064273-B1 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | UPJOHN CO (US) | 2002-12-18 | — | — | EP | disclosed |