SCHEMBL28877338

SCHEMBL28877338

C=C(C)C(=O)N(C)S(=O)(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.59
KMT2A Q03164 2/20 0.50
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 2/20 0.43
APOBEC3G Q9HC16 1/20 0.42
TSHR P16473 1/20 0.42
NR1I2 O75469 1/20 0.41
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
BCAT1 P54687 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28877340 0.84 ALDH1A1 (0.50) HSD11B1LMNAHTTALDH1A1KDM4E
SCHEMBL7924228 0.81 HSD11B1 (0.67) HSD11B1KMT2ALMNAHTTALDH1A1
SCHEMBL29150781 0.79 KMT2A (0.65) HSD11B1KMT2ALMNAALDH1A1KDM4E
SCHEMBL6425280 0.79 HSD11B1 (0.69) HSD11B1KMT2ALMNAHTTALDH1A1
SCHEMBL28877353 0.78 KMT2A (0.46) HSD11B1KMT2ALMNAHTTALDH1A1
SCHEMBL23475301 0.76 HSD11B1 (0.56) HSD11B1KMT2ALMNAHTTALDH1A1
SCHEMBL31220506 0.76 HSD11B1 (0.61) HSD11B1KMT2AHTTMEN1MAPT
SCHEMBL27540835 0.76 HSD11B1 (0.65) HSD11B1KMT2ALMNAHTTALDH1A1
SCHEMBL10511655 0.76 HSD11B1 (0.65) HSD11B1KMT2ALMNAHTTALDH1A1
SCHEMBL12879188 0.75 HSD11B1 (0.59) HSD11B1KMT2ALMNAHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121850929-A Arylsulfonyl Indolones photoinitiated cyclization synthesis method of compound 浙江工业大学 2026-04-14 CN disclosed
CN-121850909-A Photo-induced rearrangement synthesis method of sulfone compound containing amide fragment 浙江工业大学 2026-04-14 CN disclosed
CN-115260135-B Synthesis method of oxindole compound 浙江工业大学 2024-02-13 CN disclosed
CN-115260135-A Synthesis method of oxindole compound 浙江工业大学 2022-11-01 CN disclosed