Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CETP | P11597 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528551 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL2231380 | 0.82 | ALDH1A1 (0.63) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL18983569 | 0.82 | KDM4E (0.67) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL16213446 | 0.80 | KDM4E (0.65) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL18253194 | 0.79 | ALDH1A1 (0.60) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL5706504 | 0.77 | CETP (0.71) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL16210927 | 0.76 | MEN1 (0.68) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL14840612 | 0.74 | GRM5 (0.57) | KDM4EMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL2087952 | 0.74 | CETP (0.67) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL14494496 | 0.72 | ALDH1A1 (0.53) | ALDH1A1LMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109060-A | Method for selectively synthesizing quinoline-2-ketone by copper-catalyzed alpha-bromocarbonyl alkyne and maleimide serial cyclization | 湖南警察学院 | 2022-09-27 | — | — | CN | disclosed |