Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2087952 | 0.91 | CETP (0.67) | CETPL3MBTL1KDM4ELMNAALOX12 | |
| SCHEMBL8243174 | 0.87 | CETP (0.62) | CETPL3MBTL1KDM4ELMNAALOX12 | |
| SCHEMBL2301094 | 0.87 | CETP (0.68) | CETPL3MBTL1KDM4ELMNAALOX12 | |
| SCHEMBL397003 | 0.87 | PDK1 (0.67) | CETPL3MBTL1KDM4ELMNAALOX12 | |
| SCHEMBL1524283 | 0.86 | CETP (0.61) | CETPL3MBTL1KDM4ELMNAALOX12 | |
| SCHEMBL2606754 | 0.86 | CETP (0.61) | CETPL3MBTL1KDM4ELMNAALOX12 | |
| SCHEMBL16500999 | 0.86 | CETP (0.61) | CETPL3MBTL1KDM4ELMNAALOX12 | |
| SCHEMBL3535796 | 0.86 | PDK1 (0.68) | CETPL3MBTL1LMNAALDH1A1RAB9A | |
| SCHEMBL1524281 | 0.86 | CETP (0.61) | CETPL3MBTL1KDM4ELMNAALOX12 | |
| SCHEMBL7089699 | 0.86 | RAB9A (0.71) | CETPL3MBTL1KDM4ELMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071458-A | Triamide and composition comprising the triamide | 美利肯公司 | 2018-12-21 | — | — | CN | disclosed |
| EP-1311493-B1 | SYNTHESIS OF MACROCYCLIC TETRAAMIDO LIGANDS USEFUL AS BLEACHING CATALYSTS | UNIV CARNEGIE MELLON (US) | 2006-11-02 | — | — | EP | disclosed |
| US-7060818-B2 | Synthesis of macrocyclic tetraamido compounds and new metal insertion process | CARNEGIE MELLON UNIVERSITY (US) | 2006-06-13 | — | — | US | disclosed |
| US-6992184-B2 | Macrocyclic tetraamido ligands as bleaching catalysts and synthesis thereof | CARNEGIE MELLON UNIVERSITY (US) | 2006-01-31 | — | — | US | disclosed |
| WO-2004076425-A1 | IMPROVED SYNTHESIS OF MACROCYCLIC TETRAAMIDO COMPOUNDS AND NEW METAL INSERTION PROCESS | CARNEGIE MELLON UNIVERSITY (US) | 2004-09-10 | — | — | WO | disclosed |
| US-20040167329-A1 | Synthesis of macrocyclic tetraamido compounds and new metal insertion process | CARNEGIE MELLON UNIVERSITY | 2004-08-26 | — | — | US | disclosed |
| US-20030168630-A1 | Macrocyclic tetraamido ligands as bleaching catalysts and synthesis thereof | CARNEGIE MELLON UNIVERSITY | 2003-09-11 | — | — | US | disclosed |
| US-6399272-B1 | Phenylenediamine derivative-type additive useful for a chemically amplified photoresist | HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) | 2002-06-04 | — | — | US | disclosed |
| JP-2001055361-A | PHENYLENEDIAMINE DERIVATIVE, PRODUCTION OF PHENYLENEDIAMINE DERIVATIVE, PHOTORESIST COMPOSITION, FORMATION OF PHOTORESIST PATTERN AND SEMICONDUCTOR ELEMENT | HYUNDAI ELECTRONICS IND CO LTD | 2001-02-27 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167329-A1 | Synthesis of macrocyclic tetraamido compounds and new metal insertion process | DDC, DDT, DDO | CETP 4286/4885L3MBTL1 2740/4885KDM4E 1949/4885 |
| US-20030168630-A1 | Macrocyclic tetraamido ligands as bleaching catalysts and synthesis thereof | TYR, TBCB, PPOX | CETP 2148/4885L3MBTL1 1268/4885KDM4E 3064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.