SCHEMBL28877412

SCHEMBL28877412

CC(=O)Oc1cccc(NC(=O)c2cc(O)cc(CC(=O)O)c2O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
NPC1 O15118 5/20 0.54
RAB9A P51151 5/20 0.54
HTT P42858 3/20 0.54
TP53 P04637 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
ALDH1A1 P00352 1/20 0.54
HPGD P15428 1/20 0.45
CYP3A4 P08684 1/20 0.45
KDM4E B2RXH2 1/20 0.45
GAA P10253 1/20 0.45
NLRP3 Q96P20 1/20 0.44
BCAT2 O15382 1/20 0.44
PKM P14618 2/20 0.44
POLB P06746 2/20 0.44
LMNA P02545 2/20 0.44
RECQL P46063 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
RXFP1 Q9HBX9 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28877397 0.87 GAA (0.48) KMT2AMEN1NPC1RAB9AHTT
SCHEMBL28877448 0.83 MEN1 (0.56) KMT2AMEN1NPC1RAB9AHTT
SCHEMBL30031116 0.82 NR1H4 (0.55) BCAT2
SCHEMBL23796598 0.82 NR1H4 (0.55) BCAT2
SCHEMBL28877452 0.82 TOP1 (0.43) KMT2AMEN1RAB9AALDH1A1KDM4E
SCHEMBL30030702 0.81 NPC1 (0.52) KMT2AMEN1NPC1RAB9AHTT
SCHEMBL23796668 0.81 NPC1 (0.52) KMT2AMEN1NPC1RAB9AHTT
SCHEMBL28877400 0.80 KMT2A (0.55) KMT2AMEN1NPC1RAB9AHTT
SCHEMBL23796684 0.78 BCAT2 (0.45) KMT2AMEN1ALDH1A1BCAT2PKM
SCHEMBL30030700 0.78 BCAT2 (0.45) KMT2AMEN1ALDH1A1BCAT2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115279730-A 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments OM药物公司 2022-11-01 CN claimed