Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | FADS1 | O60427 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877498 | 0.87 | LMNA (0.44) | KMT2AMEN1NPC1RAB9AHTT | |
| SCHEMBL28877426 | 0.83 | KMT2A (0.56) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL23796597 | 0.81 | TERT (0.44) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL30031710 | 0.81 | TERT (0.44) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL28957929 | 0.81 | TOP1 (0.44) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28877412 | 0.80 | KMT2A (0.55) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL30032038 | 0.79 | NPC1 (0.52) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23796560 | 0.79 | NPC1 (0.52) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28877472 | 0.77 | KMT2A (0.46) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL23796671 | 0.76 | NR1H4 (0.51) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279730-A | 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments | OM药物公司 | 2022-11-01 | — | — | CN | claimed |