Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.72 |
| ▸ | CA3 | P07451 | 2/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.72 |
| ▸ | THRB | P10828 | 2/20 | 0.72 |
| ▸ | CA6 | P23280 | 1/20 | 0.72 |
| ▸ | CASP1 | P29466 | 1/20 | 0.72 |
| ▸ | APP | P05067 | 3/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL28877657 | 0.88 | MAPT (0.57) | ALDH1A1CYP3A4CA3ALOX15HIF1A | |
| 4-Aminophenol SCHEMBL6753971 | 0.85 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CA3ALOX15HIF1A | |
| Hydroquinone SCHEMBL9580349 | 0.85 | LMNA (0.61) | ALDH1A1CYP3A4CA3ALOX15HIF1A | |
| 4-Aminophenol SCHEMBL4861305 | 0.85 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CA3ALOX15HIF1A | |
| 4-Aminophenol SCHEMBL3424 | 0.85 | — | — | |
| 4-Aminophenol SCHEMBL28616632 | 0.82 | ALDH1A1 (0.81) | ALDH1A1CYP3A4CA3ALOX15HIF1A | |
| 4-Aminophenol SCHEMBL17722390 | 0.82 | ALDH1A1 (0.81) | ALDH1A1CYP3A4CA3ALOX15HIF1A | |
| 4-Aminophenol SCHEMBL1886379 | 0.82 | — | — | |
| 4-Aminophenol SCHEMBL3897816 | 0.82 | — | — | |
| 4-Aminophenol SCHEMBL19972054 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3944632-A | Phosphoric acid anilides | CIBA-GEIGY CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |
| US-3944632-A | Phosphoric acid anilides | CIBA-GEIGY CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |